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Variability in the prevalence of adult ADHD in treatment seeking substance use disorder patients: Results from an international multi-center study exploring DSM-IV and DSM-5 criteria☆☆

Identifieur interne : 004409 ( Main/Exploration ); précédent : 004408; suivant : 004410

Variability in the prevalence of adult ADHD in treatment seeking substance use disorder patients: Results from an international multi-center study exploring DSM-IV and DSM-5 criteria☆☆

Auteurs : Geurt Van De Glind [Pays-Bas] ; Maija Konstenius [Suède] ; Maarten W. J. Koeter [Pays-Bas] ; Katelijne Van Emmerik-Van Oortmerssen [Pays-Bas] ; Pieter-Jan Carpentier [Pays-Bas] ; Sharlene Kaye [Australie] ; Louisa Degenhardt [Australie] ; Arvid Skutle [Norvège] ; Johan Franck [Suède] ; Eli-Torild Bu [Norvège] ; Franz Moggi [Suisse] ; Geert Dom [Belgique] ; Sofie Verspreet [Belgique] ; Zsolt Demetrovics [Hongrie] ; Máté Kapitány-Fövény [Hongrie] ; Melina Fatséas [France] ; Marc Auriacombe [France] ; Arild Schillinger [Norvège] ; Merete M Ller [Norvège] ; Brian Johnson [États-Unis] ; Stephen V. Faraone [États-Unis] ; J. Antoni Ramos-Quiroga [Espagne] ; Miguel Casas [Espagne] ; Steve Allsop [Australie] ; Susan Carruthers [Australie] ; Robert A. Schoevers [Pays-Bas] ; Sara Wallhed [Suède] ; Csaba Barta [Hongrie] ; Peter Alleman [Suisse] ; Frances R. Levin [États-Unis] ; Wim Van Den Brink [Pays-Bas]

Source :

RBID : PMC:4133781

Descripteurs français

English descriptors

Abstract

Background

Available studies vary in their estimated prevalence of attention deficit/hyperactivity disorder (ADHD) in substance use disorder (SUD) patients, ranging from 2 to 83%. A better understanding of the possible reasons for this variability and the effect of the change from DSM-IV to DSM-5 is needed.

Methods

A two stage international multi-center, cross-sectional study in 10 countries, among patients form inpatient and outpatient addiction treatment centers for alcohol and/or drug use disorder patients. A total of 3558 treatment seeking SUD patients were screened for adult ADHD. A subsample of 1276 subjects, both screen positive and screen negative patients, participated in a structured diagnostic interview.

Results

Prevalence of DSM-IV and DSM-5 adult ADHD varied for DSM-IV from 5.4% (CI 95%: 2.4–8.3) for Hungary to 31.3% (CI 95%:25.2–37.5) for Norway and for DSM-5 from 7.6% (CI 95%: 4.1–11.1) for Hungary to 32.6% (CI 95%: 26.4–38.8) for Norway. Using the same assessment procedures in all countries and centers resulted in substantial reduction of the variability in the prevalence of adult ADHD reported in previous studies among SUD patients (2–83%→ 5.4–31.3%). The remaining variability was partly explained by primary substance of abuse and by country (Nordic versus non-Nordic countries). Prevalence estimates for DSM-5 were slightly higher than for DSM-IV.

Conclusions

Given the generally high prevalence of adult ADHD, all treatment seeking SUD patients should be screened and, after a confirmed diagnosis, treated for ADHD since the literature indicates poor prognoses of SUD in treatment seeking SUD patients with ADHD.


Url:
DOI: 10.1016/j.drugalcdep.2013.09.026
PubMed: 24156882
PubMed Central: 4133781


Affiliations:


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<wicri:regionArea>Melbourne School of Population and Global Health, University of Melbourne</wicri:regionArea>
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<settlement type="city">Melbourne</settlement>
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<orgName type="university">Université de Melbourne</orgName>
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<country xml:lang="fr">Suède</country>
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<settlement type="city">Budapest</settlement>
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<nlm:aff id="A12">Laboratoire de psychiatrie, Sanpsy CNRS USR 3413, Université de Bordeaux, and Département d’addictologie, CH Ch. Perrens/CHU de Bordeaux, Bordeaux, France</nlm:aff>
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<name sortKey="Johnson, Brian" sort="Johnson, Brian" uniqKey="Johnson B" first="Brian" last="Johnson">Brian Johnson</name>
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<nlm:aff id="A14">Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA</nlm:aff>
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<name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name>
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<nlm:aff id="A14">Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA</nlm:aff>
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<name sortKey="Ramos Quiroga, J Antoni" sort="Ramos Quiroga, J Antoni" uniqKey="Ramos Quiroga J" first="J. Antoni" last="Ramos-Quiroga">J. Antoni Ramos-Quiroga</name>
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<country xml:lang="fr">Espagne</country>
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<name sortKey="Casas, Miguel" sort="Casas, Miguel" uniqKey="Casas M" first="Miguel" last="Casas">Miguel Casas</name>
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<nlm:aff id="A15">Servei de Psiquiatria, Hospital Universitari Vall d’Hebron, CIBERSAM, Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain</nlm:aff>
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<name sortKey="Allsop, Steve" sort="Allsop, Steve" uniqKey="Allsop S" first="Steve" last="Allsop">Steve Allsop</name>
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<nlm:aff id="A16">National Drug Research Institute/Curtin University of Technology, Perth, Australia</nlm:aff>
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<name sortKey="Carruthers, Susan" sort="Carruthers, Susan" uniqKey="Carruthers S" first="Susan" last="Carruthers">Susan Carruthers</name>
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<nlm:aff id="A16">National Drug Research Institute/Curtin University of Technology, Perth, Australia</nlm:aff>
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<name sortKey="Schoevers, Robert A" sort="Schoevers, Robert A" uniqKey="Schoevers R" first="Robert A." last="Schoevers">Robert A. Schoevers</name>
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<name sortKey="Wallhed, Sara" sort="Wallhed, Sara" uniqKey="Wallhed S" first="Sara" last="Wallhed">Sara Wallhed</name>
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<name sortKey="Barta, Csaba" sort="Barta, Csaba" uniqKey="Barta C" first="Csaba" last="Barta">Csaba Barta</name>
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<nlm:aff id="A19">Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary</nlm:aff>
<country xml:lang="fr">Hongrie</country>
<wicri:regionArea>Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest</wicri:regionArea>
<placeName>
<settlement type="city">Budapest</settlement>
<region nuts="2">Hongrie centrale</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Alleman, Peter" sort="Alleman, Peter" uniqKey="Alleman P" first="Peter" last="Alleman">Peter Alleman</name>
<affiliation wicri:level="1">
<nlm:aff id="A20">Alcohol Treatment Research, Kirchlindach and Ellikon, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Alcohol Treatment Research, Kirchlindach and Ellikon</wicri:regionArea>
<wicri:noRegion>Kirchlindach and Ellikon</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Levin, Frances R" sort="Levin, Frances R" uniqKey="Levin F" first="Frances R." last="Levin">Frances R. Levin</name>
<affiliation wicri:level="2">
<nlm:aff id="A4">Columbia University/New York State Psychiatric Institute, New York City, NY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Columbia University/New York State Psychiatric Institute, New York City, NY</wicri:regionArea>
<placeName>
<region type="state">État de New York</region>
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</author>
<author>
<name sortKey="Van Den Brink, Wim" sort="Van Den Brink, Wim" uniqKey="Van Den Brink W" first="Wim" last="Van Den Brink">Wim Van Den Brink</name>
<affiliation wicri:level="4">
<nlm:aff id="A2">Amsterdam Institute for Addiction Research, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Amsterdam Institute for Addiction Research, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea>
<placeName>
<settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
<settlement type="city">Amsterdam</settlement>
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<orgName type="university">Université d'Amsterdam</orgName>
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</author>
</analytic>
<series>
<title level="j">Drug and alcohol dependence</title>
<idno type="ISSN">0376-8716</idno>
<idno type="eISSN">1879-0046</idno>
<imprint>
<date when="2013">2013</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Attention Deficit Disorder with Hyperactivity (diagnosis)</term>
<term>Attention Deficit Disorder with Hyperactivity (epidemiology)</term>
<term>Attention Deficit Disorder with Hyperactivity (therapy)</term>
<term>Cross-Sectional Studies</term>
<term>Diagnostic and Statistical Manual of Mental Disorders</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Internationality</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Prevalence</term>
<term>Substance-Related Disorders (diagnosis)</term>
<term>Substance-Related Disorders (epidemiology)</term>
<term>Substance-Related Disorders (therapy)</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Diagnostic and stastistical manual of mental disorders (USA)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Internationalité</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Résultat thérapeutique</term>
<term>Trouble déficitaire de l'attention avec hyperactivité ()</term>
<term>Trouble déficitaire de l'attention avec hyperactivité (diagnostic)</term>
<term>Trouble déficitaire de l'attention avec hyperactivité (épidémiologie)</term>
<term>Troubles liés à une substance ()</term>
<term>Troubles liés à une substance (diagnostic)</term>
<term>Troubles liés à une substance (épidémiologie)</term>
<term>Études de suivi</term>
<term>Études longitudinales</term>
<term>Études transversales</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Attention Deficit Disorder with Hyperactivity</term>
<term>Substance-Related Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Trouble déficitaire de l'attention avec hyperactivité</term>
<term>Troubles liés à une substance</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Attention Deficit Disorder with Hyperactivity</term>
<term>Substance-Related Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Attention Deficit Disorder with Hyperactivity</term>
<term>Substance-Related Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Trouble déficitaire de l'attention avec hyperactivité</term>
<term>Troubles liés à une substance</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Cross-Sectional Studies</term>
<term>Diagnostic and Statistical Manual of Mental Disorders</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Internationality</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Prevalence</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Diagnostic and stastistical manual of mental disorders (USA)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Internationalité</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Résultat thérapeutique</term>
<term>Trouble déficitaire de l'attention avec hyperactivité</term>
<term>Troubles liés à une substance</term>
<term>Études de suivi</term>
<term>Études longitudinales</term>
<term>Études transversales</term>
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<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Background</title>
<p id="P3">Available studies vary in their estimated prevalence of attention deficit/hyperactivity disorder (ADHD) in substance use disorder (SUD) patients, ranging from 2 to 83%. A better understanding of the possible reasons for this variability and the effect of the change from DSM-IV to DSM-5 is needed.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P4">A two stage international multi-center, cross-sectional study in 10 countries, among patients form inpatient and outpatient addiction treatment centers for alcohol and/or drug use disorder patients. A total of 3558 treatment seeking SUD patients were screened for adult ADHD. A subsample of 1276 subjects, both screen positive and screen negative patients, participated in a structured diagnostic interview.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P5">Prevalence of DSM-IV and DSM-5 adult ADHD varied for DSM-IV from 5.4% (CI 95%: 2.4–8.3) for Hungary to 31.3% (CI 95%:25.2–37.5) for Norway and for DSM-5 from 7.6% (CI 95%: 4.1–11.1) for Hungary to 32.6% (CI 95%: 26.4–38.8) for Norway. Using the same assessment procedures in all countries and centers resulted in substantial reduction of the variability in the prevalence of adult ADHD reported in previous studies among SUD patients (2–83%→ 5.4–31.3%). The remaining variability was partly explained by primary substance of abuse and by country (Nordic versus non-Nordic countries). Prevalence estimates for DSM-5 were slightly higher than for DSM-IV.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P6">Given the generally high prevalence of adult ADHD, all treatment seeking SUD patients should be screened and, after a confirmed diagnosis, treated for ADHD since the literature indicates poor prognoses of SUD in treatment seeking SUD patients with ADHD.</p>
</sec>
</div>
</front>
<back>
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<list>
<country>
<li>Australie</li>
<li>Belgique</li>
<li>Espagne</li>
<li>France</li>
<li>Hongrie</li>
<li>Norvège</li>
<li>Pays-Bas</li>
<li>Suisse</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
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<li>Aquitaine</li>
<li>Catalogne</li>
<li>Groningue (province)</li>
<li>Hollande-Septentrionale</li>
<li>Hongrie centrale</li>
<li>Nouvelle-Aquitaine</li>
<li>Nouvelle-Galles du Sud</li>
<li>Svealand</li>
<li>Utrecht (province)</li>
<li>Victoria (État)</li>
<li>État de New York</li>
</region>
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<li>Amsterdam</li>
<li>Barcelone</li>
<li>Bordeaux</li>
<li>Budapest</li>
<li>Groningue</li>
<li>Melbourne</li>
<li>Stockholm</li>
<li>Sydney</li>
<li>Utrecht</li>
</settlement>
<orgName>
<li>Université autonome de Barcelone</li>
<li>Université d'Amsterdam</li>
<li>Université de Bordeaux</li>
<li>Université de Melbourne</li>
</orgName>
</list>
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<name sortKey="Wallhed, Sara" sort="Wallhed, Sara" uniqKey="Wallhed S" first="Sara" last="Wallhed">Sara Wallhed</name>
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<country name="Australie">
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<name sortKey="Kaye, Sharlene" sort="Kaye, Sharlene" uniqKey="Kaye S" first="Sharlene" last="Kaye">Sharlene Kaye</name>
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<name sortKey="Allsop, Steve" sort="Allsop, Steve" uniqKey="Allsop S" first="Steve" last="Allsop">Steve Allsop</name>
<name sortKey="Carruthers, Susan" sort="Carruthers, Susan" uniqKey="Carruthers S" first="Susan" last="Carruthers">Susan Carruthers</name>
<name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name>
<name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name>
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<name sortKey="Verspreet, Sofie" sort="Verspreet, Sofie" uniqKey="Verspreet S" first="Sofie" last="Verspreet">Sofie Verspreet</name>
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<country name="Hongrie">
<region name="Hongrie centrale">
<name sortKey="Demetrovics, Zsolt" sort="Demetrovics, Zsolt" uniqKey="Demetrovics Z" first="Zsolt" last="Demetrovics">Zsolt Demetrovics</name>
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<name sortKey="Barta, Csaba" sort="Barta, Csaba" uniqKey="Barta C" first="Csaba" last="Barta">Csaba Barta</name>
<name sortKey="Kapitany Foveny, Mate" sort="Kapitany Foveny, Mate" uniqKey="Kapitany Foveny M" first="Máté" last="Kapitány-Fövény">Máté Kapitány-Fövény</name>
<name sortKey="Kapitany Foveny, Mate" sort="Kapitany Foveny, Mate" uniqKey="Kapitany Foveny M" first="Máté" last="Kapitány-Fövény">Máté Kapitány-Fövény</name>
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<country name="France">
<region name="Nouvelle-Aquitaine">
<name sortKey="Fatseas, Melina" sort="Fatseas, Melina" uniqKey="Fatseas M" first="Melina" last="Fatséas">Melina Fatséas</name>
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<name sortKey="Auriacombe, Marc" sort="Auriacombe, Marc" uniqKey="Auriacombe M" first="Marc" last="Auriacombe">Marc Auriacombe</name>
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<country name="États-Unis">
<region name="État de New York">
<name sortKey="Johnson, Brian" sort="Johnson, Brian" uniqKey="Johnson B" first="Brian" last="Johnson">Brian Johnson</name>
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<name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name>
<name sortKey="Levin, Frances R" sort="Levin, Frances R" uniqKey="Levin F" first="Frances R." last="Levin">Frances R. Levin</name>
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<country name="Espagne">
<region name="Catalogne">
<name sortKey="Ramos Quiroga, J Antoni" sort="Ramos Quiroga, J Antoni" uniqKey="Ramos Quiroga J" first="J. Antoni" last="Ramos-Quiroga">J. Antoni Ramos-Quiroga</name>
</region>
<name sortKey="Casas, Miguel" sort="Casas, Miguel" uniqKey="Casas M" first="Miguel" last="Casas">Miguel Casas</name>
</country>
</tree>
</affiliations>
</record>

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